Easy ultrastructural insight into the internal morphology of biological specimens by Atomic Force Microscopy

Paper summary

As a topographical technique, Atomic Force Microscopy (AFM) needs to establish direct interactions between a given sample and the measurement probe in order to create imaging information. The elucidation of internal features of organisms, tissues and cells by AFM has therefore been a challenging process in the past. The study at hand shows the applicability of the proposed protocol to exemplary biological samples, the resolution currently allowed by the approach as well as advantages and shortcomings compared to classical ultrastructural microscopic techniques like electron microscopy.

Journal : Nature

Publiosh Date : 13 May 2021

Paper link

Easy ultrastructural insight into the internal morphology of biological specimens by Atomic Force Microscopy