DNA carries the genetic information inside the cells and represents a sensitive target of ionizing radiation. Ionizing radiations induce free radicals in DNA constituents and thereby produce various types of DNA lesions such as base damage, DNA single-strand breaks (SSBs), DNA doublestrand breaks (DSBs), and DNA-protein crosslinks Ionizing radiation produces clustered DNA damage that contains two or more lesions in 10–20 bp.
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